Our new article on In-situ observation of the initiation of plasticity by nucleation of prismatic dislocation loops (open access) is now published in Nature Communications [Lee et al. Nat. Commun. 11, 2367 (2020)]. This work propose an in-depth description of the formation of prismatic dislocation loops in metallic nanowires, by the combination of in-situ electron microscopy and large scale atomistic simulation. My contribution to the numercial part of this work has been carried out at the FAU Erlangen-Nürnberg in the group of Prof. E. Bitzek.